В ТопКу (топовую курилку - флудилку со стаффом и баблом), конкурсы от 3 г., каждые 10 тыс сообщений = 100$

[Irishka]

А тебе дружеские объятия

втроем растопили

 

[ayaava]

Шо за павзи альо

 

[Zeno]

великий лебовськи

 

[ayaava]

втроем растопили

Холодно ещё

 

[Zeno]

там чувак той

 

[Devil]

Ебать вы пишите, можно было на той неделе еще добить

 

[Zeno]

з килимом

 

[taiga]

Buprenorphine is a semi-synthetic opioid derived from thebaine which is typically used for treatment of opioid addiction. It is an analgesic, and has gained notoriety for its ability to successfully interrupt severe opiate addictions. Buprenorphine has a higher affinity for μ-opioid receptors compared to full opioid agonists. Because of this, buprenorphine can block the effects of other opioid agonists in a dose-dependent fashion. By its dual effects of reducing craving and attenuating the response to administered heroin, buprenorphine reduces the self-administration of heroin. Methadone, a full opioid agonist, also reduces the impact of additional heroin, but the effect of methadone is primarily due to the induction of cross-tolerance which is dose dependent. In contrast buprenorphine achieves its effect primarily by prolonged occupancy of a high proportion of opioid receptors, blocking the action of heroin and other opioid receptor agonists.

 

[ayaava]

великий лебовськи

Не великий хуй

 

[Zeno]

Ебать вы пишите, можно было на той неделе еще добить

база

 

[Irishka]

да никто не хотел

 

[ayaava]

Buprenorphine is a semi-synthetic opioid derived from thebaine which is typically used for treatment of opioid addiction. It is an analgesic, and has gained notoriety for its ability to successfully interrupt severe opiate addictions. Buprenorphine has a higher affinity for μ-opioid receptors compared to full opioid agonists. Because of this, buprenorphine can block the effects of other opioid agonists in a dose-dependent fashion. By its dual effects of reducing craving and attenuating the response to administered heroin, buprenorphine reduces the self-administration of heroin. Methadone, a full opioid agonist, also reduces the impact of additional heroin, but the effect of methadone is primarily due to the induction of cross-tolerance which is dose dependent. In contrast buprenorphine achieves its effect primarily by prolonged occupancy of a high proportion of opioid receptors, blocking the action of heroin and other opioid receptor agonists.

It’s okay
Go later

 

[Noir Novelist]

а

Не пиши тут больше такое.

 

[Devil]

7911 смс в топке

 

[Irishka]

сейчас припекло

 

[ayaava]

Frankivsk city

 

[Zeno]

Не великий хуй

треба буду осмислять

 

[ayaava]

7911 смс в топке

Great result

 

[Zeno]

шо тут

 

[Irishka]

Не пиши тут больше такое.

тоже ничего не поняла